Carmeda BioActive Surface (also known as the CBAS Heparin Surface) is a registered, clinically proven technology for improvement of the performance of artificial materials used in blood-contacting medical devices.

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Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology. Follow the link below for an extensive list of publications on CARMEDA ® BioActive Surface (also known as CBAS ® Heparin Surface). The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment.

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[Reference list] On all CBAS-ePTFE grafts, heparin activity levels ranged from 15-25 pmol/cm 2 and did not differ significantly (p > 40.05). Discussion: these results support the conclusion that a stable, CBAS-ePTFE surface provides improved thromboresistance and improved patency in canine interposition models. Carmeda built quality into our technology by integrating quality assurance into all our activities, from research and product development to manufacturing, training, and documentation. Our quality management system meets the requirements of both the FDA’s Quality System Regulation 21 CFR Part 820 Skip to main content Carmeda® BioActive Surface (also known as CBAS® Heparin Surface) Reference List.

CBAS is a trademark of Carmeda AB, a wholly owned subsidiary of W. L. Gore & Associates, Inc. Featured Gore Products with CBAS Heparin Surface GORE ® PROPATEN ® Vascular Graft 50% reduction in the risk of graft occlusion compared to standard ePTFE in Critical Limb Ischemia (CLI) patients 1 Watch CBS television online.

CARMEDA® BioActive Surface (CBAS® Heparin Surface) is clinically proven hemocompatible surface coating available on the market. State of ownership, Private

Carmeda® BioActive Surface (also known as CBAS® Heparin Surface) Reference List. Upplands Väsby, Sweden: Carmeda AB; 2019. [Reference list] On all CBAS-ePTFE grafts, heparin activity levels ranged from 15-25 pmol/cm 2 and did not differ significantly (p > 40.05).

The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment. This proprietary coupling technique is the key to thromboresistance and long-term stability.

The CARMEDA ® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices. It is the most clinically proven thromboresistant surface coating available on the market. The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment.

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The CARMEDA ® BioActive Surface is marketed under the trademark CBAS ® Heparin Surface for GORE ® Vascular Devices. CBAS ® Heparin Surface The CARMEDA ® BioActive Surface is licensed to major medical device companies worldwide. Below is a selection of currently approved The CARMEDA ® BioActive Surface (also known as CBAS ® Heparin Surface) is a mature technology with an impressive pre-clinical and clinical track record. Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology. Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology.

Evaluation of Carmeda bioactive surface (CBAS), Duraflo II and a novel nonspecific protease-modified surface using a new in vitro model simulating cardiopulmonary bypass. Yii M(1), Gourlay T, Fleming J, Matata B, Taylor KM. Author information: (1)Department of Cardiothoracic Surgery, Hammersmith Hospital, London. PMID: 8817631 [Indexed for MEDLINE] Carmeda BioActive Surface (also known as the CBAS Heparin Surface) is a registered, clinically proven technology for improvement of the performance of artificial materials used in blood-contacting medical devices. Carmeda built quality into our technology by integrating quality assurance into all our activities, from research and product development to manufacturing, training, and documentation.
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The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces. The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies and scientific papers:

Abbreviation The durability of CBAS Heparin Surface on EXCOR pumps retrieved after clinical use for varying periods of time was studied by analyzing samples for surface heparin density and bioactivity. The mean time of clinical use of the investigated 14 EXCOR pumps was 178 days (range, 15-461 days).

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End-point covalent bonding keeps heparin anchored to the device, while the bioactive site remains free to interact with the blood to help prevent clotting. 2017-03-01 · CARMEDA ® BioActive Surface (CBAS ® Heparin Surface) This heparin bonding technology was developed by Carmeda AB, a wholly owned subsidiary of W.L. Gore & Associates, Inc. The technology has been used in a variety of applications including CPB equipment, hemodialysis catheters, ventricular assist devices, vascular stents, stent grafts, and vascular grafts. Evaluation of Carmeda bioactive surface (CBAS), Duraflo II and a novel nonspecific protease-modified surface using a new in vitro model simulating cardiopulmonary bypass. Yii M(1), Gourlay T, Fleming J, Matata B, Taylor KM. Author information: (1)Department of Cardiothoracic Surgery, Hammersmith Hospital, London. PMID: 8817631 [Indexed for MEDLINE] Carmeda BioActive Surface (also known as the CBAS Heparin Surface) is a registered, clinically proven technology for improvement of the performance of artificial materials used in blood-contacting medical devices.